This is Part 5 of the Main Story Walkthrough . Finish The Six Assemble first — the Raft should already have broken open.
This chapter covers Act 3 from …Into the Fire through Pax in Bello.
Precincts and poison
…Into the Fire splits the map: Electro at one precinct, Rhino at the other. Clear both objectives. Street crimes during quarantine are noise; the yellow list is the cure path.
Picking Up the Trail uses the spectrograph, then a double boss — Electro and Vulture. Restock gadgets before the fight. Web and dodge windows matter more than dumping every suit power at once.
Streets of Poison — Scorpion floods Central Park. Stay off the water. Grab the antiserum parts the mission names.
Supply Run — Miles stealth through a Sable/prisoner mess for the last components. No web-shooters heroics; play it as stealth.
Heavy Hitter — Rhino, then Rhino and Scorpion together. Keep moving; standing in charge lanes is how the fight pads out.
Osborn, Li, Octavius
Step Into My Parlor… — MJ in Norman Osborn’s penthouse. Keypad, secret room, the real location. Play the MJ section; skipping it breaks the next marker’s context.
The Heart of the Matter — F.E.A.S.T., Mister Negative, Devil’s Breath. This is the human ending of the Li plot. Watch it.
Pax in Bello — Doctor Octopus on the tower. Anti-Ock Suit. That is the last main-campaign beat. Credits after. Do not start The City That Never Sleeps until this mission is done.
After the credits
Safe completion targets before DLC:
- Remaining towers, backpacks, landmarks, research stations
- Side missions still open on the map
- Taskmaster challenges if you skipped timers
Then move to The City That Never Sleeps — Heist, Turf Wars, Silver Lining in release order.
What to do next
DLC chapter: The City That Never Sleeps . Hub: Marvel’s Spider-Man (2018) . Next Insomniac story after DLC: Miles Morales .